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Stat3多克隆抗体

货号 品牌 CAS 规格 销售价(RMB) 折扣价(RMB) 备注 数量
ABP0124-100μL Abbkine 100μL 1998 1998
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商品信息

产品英文名称Stat3 Polyclonal Antibody
免疫原合成多肽:人源Stat3 非磷酸化位点为中心:Y705
宿主
反应性人, 大鼠, 小鼠
应用ELISA, IF, IHC-P, WB
实验建议最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比为:WB:1:500-1:2000,IF:1:50-1:200,IHC-P:1:100-1:300,ELISA:1:5000。
克隆性多克隆
纯化工艺使用表位特异性的免疫原,通过亲和层析,从兔抗血清中亲和纯化抗体。

商品属性

产品形式液体溶液
浓度1 mg/ml
分子量88 KD
储存缓冲液PBS缓冲液(pH 7.4),含有0.5%BSA(稳定剂),0.02%叠氮化钠(防腐剂)和50%甘油。
保存建议自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。
运输条件蓝冰运输
警告本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。

附加信息

背景Signal transducer and activator of transcription 3 encoded by STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
基因ID6774
别名STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor
其它该抗体可检测内源蛋白
蛋白质IDP40763