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E-cadherin多克隆抗体

货号 品牌 CAS 规格 销售价(RMB) 折扣价(RMB) 备注 数量
ABP0083-100μL Abbkine 100μL 1998 1998
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商品信息

产品英文名称E-cadherin Polyclonal Antibody
免疫原合成多肽:人源蛋白的C末端,E-cadherin,AA:810-890
宿主
反应性人, 大鼠, 小鼠
应用ELISA, IF, IHC-P, WB
实验建议最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比为:WB:1:500-1:2000,IF:1:200-1:1000,IHC-P:1:100-1:300,ELISA:1:20000。
克隆性多克隆
纯化工艺使用表位特异性的免疫原,通过亲和层析,从兔抗血清中亲和纯化抗体。

商品属性

产品形式液体溶液
浓度1 mg/ml
分子量125-130 KD
储存缓冲液PBS缓冲液(pH 7.4),含有0.5%BSA(稳定剂),0.02%叠氮化钠(防腐剂)和50%甘油。
保存建议自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。
运输条件蓝冰运输
警告本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。

附加信息

背景CDH1 encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in CDH1 are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. CDH1 is present in a gene cluster with other members of the cadherin family on chromosome 16.
基因ID999/1000/1001/1002
别名CDH1; CDHE; UVO; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324; CDH2; CDHN; NCAD; Cadherin-2; CDw325; Neural cadherin; N-cadherin; CD antigen CD325; CDH3; CDHP; Cadherin-3; Placental cadherin; P-cadhe
其它该抗体可检测内源蛋白
蛋白质IDP12830/P19022/P22223/P55283