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p38 (磷酸化-Thr180/Y182)多克隆抗体

货号 品牌 CAS 规格 销售价(RMB) 折扣价(RMB) 备注 数量
ABP0047-100μL Abbkine 100μL 1998 1998
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商品信息

产品英文名称p38 (phospho Thr180/Y182) Polyclonal Antibody
免疫原合成多肽:人源p38 磷酸化位点为中心:T180/Y182
宿主
反应性人, 大鼠, 小鼠, 豚鼠
应用ELISA, IF, IHC-P, WB
实验建议最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比为:WB:1:500-1:2000,IF:1:50-1:200,IHC-P:1:100-1:300,ELISA:1:5000。
克隆性多克隆
纯化工艺使用表位特异性的免疫原,通过亲和层析,从兔抗血清中亲和纯化抗体。

商品属性

产品形式液体溶液
浓度1 mg/ml
分子量38 KD
储存缓冲液PBS缓冲液(pH 7.4),含有0.5%BSA(稳定剂),0.02%叠氮化钠(防腐剂)和50%甘油。
保存建议自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。
运输条件蓝冰运输
警告本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。

附加信息

背景Mitogen-activated protein kinase 14 encoded by MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. Mitogen-activated protein kinase 14 is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs, or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with mitogen-activated protein kinase 14.The substrates of mitogen-activated protein kinase 14 include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of mitogen-activated protein kinase 14 in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of MAPK14 encoding distinct isoforms have been reported.
基因ID1432
别名MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein
其它该抗体可检测内源蛋白
蛋白质IDQ16539