货号 | 品牌 | CAS | 规格 | 销售价(RMB) | 折扣价(RMB) | 备注 | 数量 |
ABP0041-100μL | Abbkine | 无 | 100μL | 1998 | 1998 | 无 |
产品英文名称 | JNK1/2/3 (phospho Thr183) Polyclonal Antibody |
免疫原 | 合成多肽:人源JNK1/2/3 磷酸化位点为中心:T183 |
宿主 | 兔 |
反应性 | 人, 大鼠, 小鼠 |
应用 | ELISA, IF, IHC-P, WB |
实验建议 | 最佳的工作稀释比例需要客户摸索优化。建议的起始尝试的稀释比为:WB:1:500-1:2000,IF:1:200-1:1000,IHC-P:1:100-1:300,ELISA:1:5000。 |
克隆性 | 多克隆 |
纯化工艺 | 使用表位特异性的免疫原,通过亲和层析,从兔抗血清中亲和纯化抗体。 |
产品形式 | 液体溶液 |
浓度 | 1 mg/ml |
分子量 | 54 KD |
储存缓冲液 | PBS缓冲液(pH 7.4),含有0.5%BSA(稳定剂),0.02%叠氮化钠(防腐剂)和50%甘油。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
背景 | Mitogen-activated protein kinase 8 encoded by MAPK8 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. Mitogen-activated protein kinase 8 is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. Mitogen-activated protein kinase 8 is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of MAPK8 suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. |
基因ID | 5599/5601/5602 |
别名 | MAPK8; JNK1; PRKM8; SAPK1; SAPK1C; Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK9; JNK2; PRKM9; SAPK1A; Mi |
其它 | 该抗体可检测内源蛋白 |
蛋白质ID | P45983/P45984/P53779 |
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